SpheriTech Limited – ‘New solutions through innovation’

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CAR T-cell therapy (27th August 2019)

Chimeric antigen receptor T-cells (CAR T cells) are T-cells where the DNA has been engineered to produce a modified T-cell receptor for use in immunotherapy.  The T-cells are normally captured and activated using polystyrene based magnetic microparticles, which are expensive and can cause issues during T-cell isolation for return to the donor.  At Spheritech we are developing a macroporous biopolymer cartridge with immobilised antibodies for T-cell activation.  This simplifies the whole process from activation through to T-cell recovery.  We hope to launch a range of T-cell activation cartridges in the next 6-8 months.


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